Yellow Fever: Virology, Clinical Features and Management

Yellow fever taught from the virus outwards: an enveloped single-stranded RNA flavivirus with three genotypes, urban and jungle transmission cycles, Kenya's low-risk status and its last outbreak in 1992, the liver, heart, kidney and brain damage of pathogenesis, the two-phase clinical picture with jaundice and haemorrhage, laboratory findings, diagnosis on travel history and antigen detection, supportive management that avoids hepatotoxic and nephrotoxic drugs, complications, and the 17D live-attenuated vaccine with its dose, ten-year travel certification and contraindications.