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Diploma in Clinical Medicine and Surgery
Diabetic Ketoacidosis: Precipitating Factors, Pathophysiology and Management
A teaching deck on DKA as an acute, life-threatening complication of diabetes marked by hyperglycaemia, ketoacidosis and ketonuria. It covers the precipitating factors from new diagnosis and omitted insulin to infection, pregnancy and emotional stress, the pathophysiology of insulin deficiency with unsuppressed adipose lipase and hepatic ketone production, the history, signs and biochemical parameters, then management through isotonic normal saline, a continuous intravenous insulin infusion, potassium replacement, sodium bicarbonate, and hourly blood sugar, vital-sign and mental-status monitoring.
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